应用
Tolbutamide, have been used in a cDNA microarray assay to probe changes in gene expression in HepG2 cells upon their administration. It has been utilized to counteract insulin activity in a patch-clamp investigation of ATP sensitive K+ channels in mouse pancreatic β-cells. The activity of various biotransformation enzymes in cultured primary rat proximal tubular cells in the presence of tolbutamide and other compounds has been studied.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

基本信息

MDL
MFCD00027169

EINECS
200-594-3

分子式
C₁₂H₁₈N₂O₃S

分子量
270.35

熔点
128-130°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in chloroform.

Beilstein
1984428

Merck
14,9507

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H317
Harmful if swallowed.May cause an allergic skin reaction.

Precautionary Statements
P261-P280g-P301+P312a-P321-P333+P313-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves.Wear protective gloves.Specific treatment (see label).If skin irritation or rash occurs: Get medical advice/attention.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
43
May cause sensitization by skin contact.

安全等级
24-37
Avoid contact with skin.

RTECS
YS4550000

TSCA
是