应用
(R)-(-)-Tetrahydrofurfurylamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors.

备注
Hygroscopic, store away from water/moisture. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

基本信息

MDL
MFCD00192476

分子式
C₅H₁₁NO

分子量
101.15

沸点
152-153°

闪点
45°(113°F)

密度
0.980

折射率
1.4550

灵敏度
Very Hygroscopic. Store under Argon. Ambient temperatures.

形态
Liquid

溶解性
Fully miscible with water.

Beilstein
4652873

GHS危害和防范说明

GHS符号

Hazard Statements
H226-H314-H318
Flammable liquid and vapour.Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P210-P260h-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Keep away from heat/sparks/open flames/hot surfaces. - No smoking.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
3

包装组
III

危险类别
10-34
Flammable.Causes burns.

安全等级
20-26-36/37/39-45
When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
否