应用
Tetraethyl methylidenediphosphonate is used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters. It acts as an intermediate for the synthesis of bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. It is also used as a reactant for synthesis of dual substrate-site inhibitors of 3-deoxy-D-arabino-heputosonate 7-phosphate synthase and alpha-amino acid derivatives containing gem-biophosphonates, Lycopene through Wittig-Horner reaction. It is also used as a precursor for the preparation of dendritic polyglycerol anions.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00039887

EINECS
216-764-5

分子式
C₉H₂₂O₆P₂

分子量
288.22

沸点
151-153°/1.2mm

闪点
>110°(230°F)

密度
1.162

折射率
1.4400

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Slightly miscible with water.

Beilstein
1813241

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319
Causes skin irritation.Causes serious eye irritation.

Precautionary Statements
P280g-P305+P351+P338
Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
36/38
Irritating to eyes and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
SZ9150000

TSCA
是