应用
Tetra-n-butylammonium fluoride trihydrate is used as a phase transfer catalyst, as a mild base and as a source of fluoride ion in organic solvents. It is also used as a deprotecting agent to remove silyl ether protecting groups. It acts as a reactant for the preparation of deprotecting agents, in preparation of cellulose derivatives, lipophilic peptides for DNA transfections in vivo and Dehydrobromination reactions. It plays an important role in the convertion of O-silylated enolates in to carbonyls in the presence of dimethyl sulfoxide.

备注
Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00149981

EINECS
207-057-2

分子式
C₁₆H₃₆FN?3H₂O

分子量
315.52 (261.47anhy)

熔点
54-60°

灵敏度
Store under Nitrogen. Hygroscopic. Ambient temperatures.

形态
Fused solid or lumps

溶解性
Soluble in water, terahydrofuran, dimethyl sulfoxide and acetonitrile.

Beilstein
3761900

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
III

危险类别
34
Causes burns.

安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
是