应用
Pinacolborane is used as a precursor of boronic esters by hydroboration or coupling reactions. It acts as a monofunctional hydroborating agent. It is used in the synthesis of unsymmetrical biaryls through aromatic C-H borylation-cross-coupling sequence. It is involved in the preparation of 4,4,5,5-tetramethyl-2-thiophen-2-yl-[1,3,2]dioxaborolane by reacting with 2-iodo-thiophene. Further, it is used to prepare vinylboronates by palladium-catalyzed coupling with alkenyl triflates and iodides.

备注
Air sensitive and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong acids, water, bases and alcohols.

基本信息

MDL
MFCD00674030

分子式
C₆H₁₃BO₂

分子量
127.98

沸点
42-43°/50mm

闪点
5°(41°F)

密度
0.882

折射率
1.3970

灵敏度
Keep Cold. Air Sensitive. Store under Argon.

形态
Liquid

溶解性
Miscible with ether, dichloromethane, tetrahydrofuran and organic solvents.

Beilstein
7802871

GHS危害和防范说明

GHS符号

Hazard Statements
H225-H261-H333-H319
Highly flammable liquid and vapour.In contact with water releases flammable gas.May be harmful if inhaled.Causes serious eye irritation.

Precautionary Statements
P223-P210-P231+P232-P303+P361+P353-P305+P351+P338-P501a
Keep away from any possible contact with water, because of violent reaction and possible flash fire.Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Handle under inert gas. Protect from moisture.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
4.3

包装组
II

危险类别
11-15-36
Highly flammable.Contact with water liberates extremely flammable gases.Irritating to eyes.

安全等级
7/8-9-16-23-26-33-43-60
Keep container tightly closed and dry.Keep container in a well-ventilated place.Keep away from sources of ignition - No smoking.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Take precautionary measures against static discharges.In case of fire, use ... (indicate in the space the precise type of fire fighting equipment. If water increases risk, odd 'Never use water')This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA
否