应用
4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.

备注
Moisture sensitive. Store in a cool place. Incompatible with water, acids, alcohols, ammonia, amines and strong bases.

基本信息

MDL
MFCD00007321

EINECS
231-706-9

分子式
C₇H₄ClNO₄

分子量
201.57

熔点
75-82°

沸点
159-162°/19mm

闪点
>110°(230°F)

灵敏度
Keep Cold. Moisture Sensitive.

形态
Solid

溶解性
Soluble in acetone, chloroform, acetone, toluene and benzene.

Beilstein
518127

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H314-H318-H335
Harmful if swallowed.Causes severe skin burns and eye damage.Causes serious eye damage.May cause respiratory irritation.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
34-37
Causes burns.Irritating to respiratory system.

安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
是