应用
2-Nitrobenzyl bromide is used in the preparation of S-2-nitrobenzyl-cysteine by reaction with L-cysteine. It is also used for the introduction of the 2-nitrobenzyl protecting group in organic synthesis. It plays an important role in the production of expectorant agent. Further, it is employed for caging unprotected cysteine-containing or thiophosphorylated peptides in aqueous solution. In addition to this, it is used in the preparation of (R)- and (S)-3-amino-3,4-dihydro-1H-quinolin-2-one.

备注
Moisture sensitive. Incompatible with alcohols, bases, amines and oxidizing agents.

基本信息

MDL
MFCD00007184

EINECS
223-558-9

分子式
C₇H₆BrNO₂

分子量
216.04

熔点
45-48°

闪点
>110°(230°F)

灵敏度
Keep Cold.

形态
Crystalline powder

溶解性
Insoluble in water.

Beilstein
638991

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318-H317
Causes severe skin burns and eye damage.Causes serious eye damage.May cause an allergic skin reaction.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
5-34-43
Heating may cause an explosion.Causes burns.May cause sensitization by skin contact.

安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
否