应用
N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg²⁺ dependent internucleosomal DNA fragmentation.

备注
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.

基本信息

MDL
MFCD00005509

EINECS
204-892-4

分子式
C₆H₇NO₂

分子量
125.13

熔点
43-46°

沸点
209-211°

闪点
73°(163°F)

灵敏度
Light Sensitive. Ambient temperatures.

形态
Crystalline

溶解性
Soluble in ethanol, water, chloroform, methanol and toluene.

Beilstein
112448

Merck
14,3822

GHS危害和防范说明

GHS符号

Hazard Statements
H300-H311-H314-H318-H317
Fatal if swallowed.Toxic in contact with skin.Causes severe skin burns and eye damage.Causes serious eye damage.May cause an allergic skin reaction.

Precautionary Statements
P260h-P301+P310a-P303+P361+P353-P305+P351+P338-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
II

危险类别
21-28-34-43
Harmful in contact with skin.Very toxic if swallowed.Causes burns.May cause sensitization by skin contact.

安全等级
20-26-28-36/37/39-45-60
When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer).Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
UX9625000

TSCA
是