应用
2-Butynoic acid is used as an intermediate in organic synthesis and pharmaceuticals. It is used as a synthon in various reactions, which includes cylcoalkylation of phenols to flavones and chromones. It is involved in the cyclization of gamma-butyrolactones. It is also used in the synthesis of Z-trisubstituted olefins through µ-alkylation. It plays an important role in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs, which finds application as anti-cancer agents.

备注
Store in a cool place. Incompatible with strong oxidizing agents, strong bases and strong reducing agents.

基本信息

MDL
MFCD00004363

EINECS
209-695-7

分子式
C₄H₄O₂

分子量
84.07

熔点
75-79°

沸点
200-203°

密度
0.964

灵敏度
Keep Cold.

形态
Crystalline powder

溶解性
Soluble in water. Slightly soluble in methanol and chloroform.

Beilstein
1740205

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P280-P305+P351+P338-P308+P313
Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or concerned: Get medical advice/attention.

安全信息

危险等级
8

包装组
II

危险类别
34
Causes burns.

安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
是