应用
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

备注
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.

基本信息

MDL
MFCD00000501

EINECS
242-042-4

分子式
C₆H₁₅ClSi

分子量
150.73

熔点
86-89°

沸点
124-126°

闪点
22°(72°F)

密度
0.81

灵敏度
Moisture Sensitive. Ambient temperatures.

形态
Crystals

溶解性
Soluble in chloroform and ethyl acetate. Insoluble in water.

Beilstein
505999

GHS危害和防范说明

GHS符号

Hazard Statements
H228-H314-H318
Flammable solid.Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P210-P280-P305+P351+P338-P309-P310a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:

安全信息

危险等级
8

包装组
I

危险类别
11-34
Highly flammable.Causes burns.

安全等级
16-26-36/37/39-45
Keep away from sources of ignition - No smoking.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

RTECS
VV2000000

TSCA
是