应用
3-Bromo-5-iodobenzoic acid may be used in the preparation of the following: • Phenyl(3-bromo-5-iodo)benzoate. • As starting reagent for the large-scale synthesis of the thromboxane receptor antagonist 3-{3-[2-(4-chlorobenzenesulfonamido)ethyl]-5-(4-fluorobenzyl)phenyl}propionic acid, via regioselective Heck cross-coupling reaction. • Methyl 3-bromo-5-iodobenzoate. • 3-Bromo-5-(triisopropylsilylethynyl)benzoic acid, via Sonogashira coupling reaction. • Trifluoroacetophenone.

备注
Light Sensitive. Protect from light. Store away from oxidizing agents.

基本信息

MDL
MFCD00191851

分子式
C₇H₄BrIO₂

分子量
326.92

熔点
218-221°

灵敏度
Light Sensitive. Ambient temperatures.

形态
Powder

溶解性
Soluble in methanol. Sparingly Soluble (0.20 g/L) (25°C), Calc.

Beilstein
3240837

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA
否