应用
It is a substrate employed in a palladium-catalyzed cross-coupling with benzylic acetates providing diarylmethanes. It is a reactant involved in Suzuki-Miyaura cross-coupling reactions with arylhalides, dibromovinyl precursors, alkenyl tosylates and mesylates, and quinoline carboxylates. It is involved in intramolecular Friedel-Crafts alkylation for synthesis of chiral tetralins, hydroxylation to phenols and oxidative coupling with alkynes.

备注
Store in cool dry conditions in well sealed containers. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00136929

分子式
C₁₂H₁₁BO₂

分子量
198.03

熔点
173-194°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Insoluble in water.

Beilstein
3031806

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA
否