应用
Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

备注
It is sensitive to moisture. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature is 2 - 8?°C. Store under inert gas.

基本信息

MDL
MFCD00010768

分子式
C₉H₉ClO₂

分子量
184.62

沸点
84-87°/0.4mm

闪点
>110°(230°F)

密度
1.189

折射率
1.5230

灵敏度
Keep Cold. Moisture Sensitive.

形态
Liquid

溶解性
Reacts with water.

Beilstein
1947363

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

UN#
UN3265

危险等级
8

包装组
II

危险类别
14-34
Reacts violently with water.Causes burns.

安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
否