应用
1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

备注
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents, acid chlorides and acid anhydrides. It is sensitive to air.

基本信息

MDL
MFCD00006516

EINECS
248-540-8

分子式
C₇H₁₆N₂

分子量
128.22

沸点
185-186°

闪点
57°(134°F)

密度
0.903

折射率
1.4740

灵敏度
Air Sensitive. Ambient temperatures.

形态
Liquid

溶解性
Partly miscible in water.

Beilstein
103469

GHS危害和防范说明

GHS符号

Hazard Statements
H226-H314-H318
Flammable liquid and vapour.Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P210-P260h-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Keep away from heat/sparks/open flames/hot surfaces. - No smoking.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
34
Causes burns.

安全等级
20-26-36/37/39-45
When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
否