应用
(Acetylmethylene)triphenylphosphorane is used as a Wittig reagent in synthetic chemistry, especially for the synthesis of functionalized pyrrolidines and cyclobutanones. It plays as a vital role in asymmetric allylboration for enantioselective synthesis of (+)-awajanomycin.It is also employed as a reactant in the preparation of 1,2-dioxanes with antitrypanosomal activity. Further, it is used in the preparation of amphibian pyrrolizidine alkaloids through allylic aminations and silicon-containing acyclic dienone musk odorants. In addition to this, it is involved in Domino Suzuki/Heck coupling reactions to prepare fluorenylidenes.

备注
Air sensitive. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00008774

EINECS
215-878-2

分子式
C₂₁H₁₉OP

分子量
318.36

熔点
204-209°

灵敏度
Keep Cold. Air Sensitive.

形态
Crystalline powder

溶解性
Soluble in chloroform. Slightly soluble in methanol.

Beilstein
750077

安全信息

RTECS
UC3900000

TSCA
否