应用
4-Acetylbutyric acid is used in the synthesis of selective indomethacin analogues for AKR1C3 inhibition in the treatment of castrate-resistant prostate cancer. It is also used to prepare PARP inhibitors for the treatment of cancer.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00004412

EINECS
221-511-7

分子式
CH₃CO(CH₂)₃CO₂H

分子量
130.14

熔点
12-14°

沸点
274-275°

闪点
>110°(230°F)

密度
1.100

折射率
1.4451

灵敏度
Ambient temperatures.

溶解性
Slightly soluble in water, chloroform and methanol.

Beilstein
385840

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319
Causes skin irritation.Causes serious eye irritation.

Precautionary Statements
P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313
Wear protective gloves and eye/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment (see label).If skin irritation occurs: Get medical advice/attention.If eye irritation persists: Get medical advice/attention.

安全信息

危险类别
36/38
Irritating to eyes and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA
是