应用
Trimethylsilyl isocyanate is used in the preparation of 1-unsubstituted 4-(dialkylamino) imidazolin-2-ones. It finds application in the carbamoylation of aromatic hydrocarbons and alcohols. It is also used in the preparation of primary amides from Grignard reagents. Further, it is used in the synthesis of cyclic imides. It is also utilized for the synthesis of trifluoroacetyl isocyanate and cyclic imides. In addition to this, it is employed in the conversion of isocyanates to carbodiimides using cyclopentadienyl Mn(CO)₃ catalysis.

备注
Moisture sensitive. Incompatible with strong oxidizing agents, acids, strong bases, alcohols and amines.

基本信息

MDL
MFCD00001993

EINECS
214-256-8

分子式
C₄H₉NOSi

分子量
115.21

熔点
-49°

沸点
90-92°

闪点
-2°(28°F)

密度
0.859

折射率
1.3960

灵敏度
Store at -20°C. Moisture Sensitive. May form a Precipitate. Store under Nitrogen.

形态
Liquid

溶解性
Miscible with ethers and o-dichlorobenzene.

Beilstein
1744962

GHS危害和防范说明

GHS符号

Hazard Statements
H225-H330-H315-H319-H334-H335
Highly flammable liquid and vapour.Fatal if inhaled.Causes skin irritation.Causes serious eye irritation.May cause allergy or asthma symptoms or breathing difficulties if inhaled.May cause respiratory irritation.

Precautionary Statements
P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment is urgent (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
3

包装组
II

危险类别
11-23-36/37/38-42
Highly flammable.Toxic by inhalation.Irritating to eyes, respiratory system and skin.May cause sensitization by inhalation.

安全等级
9-16-23-26-36/37-45
Keep container in a well-ventilated place.Keep away from sources of ignition - No smoking.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
是