应用
Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00008452

EINECS
227-663-0

分子式
C₅H₁₁O₅P

分子量
182.11

沸点
119-120°/1mm

闪点
70°(158°F)

密度
1.263

折射率
1.4370

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Slightly miscible with water.

Beilstein
1865177

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H315-H319-H335
Combustible liquid.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P210e-P261-P280a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
9-36
Keep container in a well-ventilated place.Wear suitable protective clothing.

TSCA
是