应用
2,2,6-Trimethyl-1,3-dioxin-4-one is used in the synthesis of dihydropyrimininones as picomolar sodium iodide symporter inhibitors. It is also used in the synthesis of resorcinol amide Hsp90 Inhibitor AT13387. It is used in the synthesis of acetylketene by flash pyrolysis.

备注
Store at 4?°C. Protect from heat. Store away from oxidizing agents.

基本信息

MDL
MFCD00040468

EINECS
226-403-3

分子式
C₇H₁₀O₃

分子量
142.15

熔点
7°

沸点
65-67°/2mm

闪点
14°(57°F)

密度
1.094

折射率
1.4610

灵敏度
Keep Cold.

形态
Liquid

溶解性
Soluble in Chloroform, Methanol. Not miscible in water.

Beilstein
2408

GHS危害和防范说明

GHS符号

Hazard Statements
H225-H315-H319-H335
Highly flammable liquid and vapour.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Avoid breathing dust/fume/gas/mist/vapours/spray.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
3

包装组
II

危险类别
11-36/37/38
Highly flammable.Irritating to eyes, respiratory system and skin.

安全等级
9-16-23-26-33-36/37-60
Keep container in a well-ventilated place.Keep away from sources of ignition - No smoking.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Take precautionary measures against static discharges.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA
否